Table 3.
FGF-10 immunoreactivity in exstrophy specimens with von Brunn's nests, cystitis cystica, or squamous metaplasia
| Specimen | Urothelium | Von Brunn's Nest | Cystitis Cystica | Squamous Metaplasia |
|---|---|---|---|---|
| 1 | Focal, ± | NP | − | Focal, +++ |
| 2 | NP | Focal, ± | NP | NP |
| 3 | Multifocal, +++ | Multifocal, ±; diffuse, +++ | NP | NP |
| 4 | NP | Diffuse, ± | NP | NP |
| 5 | Diffuse, +++ | NP | Focal, ± | NP |
| 6 | NP | − | NP | NP |
| 7 | NP | Diffuse, ± | NP | NP |
Tissue explants taken during the stage of the surgery listed. NP, not present. Immunoreactivity of FGF-10 in bladder exstrophy specimens that contain von Brunn's nests, cystitis cystica, or urothelium was given a subjective score by a pathologist (L. D. True) consisting of 2 dimensions: 1) the pattern of signal in cells; and 2) the strength of the signal (diffuse, focal, multifocal) and the intensity of signal in cells (−, negative, ± faint, or +++ intense).