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Developmental changes in mouse brush-border membrane NHE3 (A) and NHE8 (B) protein abundance. Brush-border membrane vesicles (BBMV) were harvested from mice from 1 day of age to adults. The relative protein abundance of NHE3 and NHE8 at the ages shown was compared relative to β-actin. As can be seen, there is a developmental increase in NHE3 and a decrease in NHE8. D, day; AD, adult; n, no. of mice.
