Fig. 4.

Summarizing figure depicting RMRt (resting metabolic rate at thermoneutrality) and maximal norepinephrine-induced heat production (NEmax) of WT and UCP1-KO mice acclimated to different ambient temperatures: WA: 27°C, MCA: 18°C; cold acclimated (CA): 5°C, and in relation to maximal cold-induced heat production (HPmax). The corresponding cold limits for each group of mice are indicated. Data are indicated as means ± SD; n = 4–7 individuals per group. Note that HPmax and NEmax were determined in two different sets of mice for each genotype. RMRt was obtained prior to the injection of norepinephrine (for details, see text).