Table 1. Clinicopathological features and gene mutation status of colorectal carcinomas for each of the three age groups.
| <50 years, n = 45 (%) | 51–70 years, n = 67 (%) | >70 years, n = 69 (%) | ||
| Age at onset of disease | Min | 27 | 51 | 71 |
| Max | 50 | 70 | 93 | |
| Mean | 41 | 61 | 80 | |
| Sex | Female | 23 (51) | 31 (46) | 36 (52) |
| Male | 22 (49) | 36 (54) | 33 (48) | |
| Tumor location in the large bowel | Right | 12 (27) | 29 (43) | 33 (48) |
| Left | 16 (36) | 15 (22) | 20 (29) | |
| Rectum | 17 (38) | 23 (34) | 16 (23) | |
| Stage | I | 5 (11) | 14 (21) | 16 (23) |
| II | 16 (36) | 22 (33) | 28 (41) | |
| III | 17 (38) | 22 (33) | 22 (32) | |
| IV | 7 (16) | 9 (13) | 3 (4) | |
| Mutations § | KRAS | 13 (30) | 20 (30) | 24 (35) |
| BRAF | 3 (7) | 12 (18) | 13 (19) | |
| PIK3CA | 0 | 5 (8) | 3 (4) | |
| PTEN * | 8 (18) | 7 (10) | 11 (16) | |
| TP53 | 29 (64) | 26 (39) | 38 (55) | |
| MSI | 6 (13) | 13 (19) | 14 (20) |
*Impaired PTEN: Combined results from sequencing and MLPA.
§
Percentages are calculated based on the number of patients with successful analyses.