Table 6.
Flow cytometric analysis and agonist-induced platelet aggregation in GT patients
| Patient | FACS analysis |
Platelet aggregation |
||||
|---|---|---|---|---|---|---|
| CD41 anti-αIIb % | PAC-1, % |
ADP (5 urnol/1) | collagen (1 μg/ml) | ristocetin (1.3 mg/ml) | ||
| 10 μmol/l ADP | 10 μmol/1 TRAP | |||||
| TA (M) | <1 | <1 | <1 | Ø | Ø | N |
| TG (M) | <1 | <1 | <1 | Ø | Ø | N |
| TN (F) | 90 | 37 | 55 | (▾) | (▾) | N |
| TF (M) | 78 | 38 | 25 | (▾) | (▾) | N |
| GE (F) | <1 | <1 | <1 | Ø | Ø | N |
| CM (F) | 58 | 44 | 51 | (▾) | ▾ | N |
| SB (F) | 23 | 13 | 12 | ▾ | (▾) | N |
| YF (M) | 3 | n.a. | n.a. | n.a. | n.a. | n.a. |
| TE (M) | <1 | <1 | <1 | Ø | Ø | N |
| DZ (F) | 0 | n.a. | n.a. | n.a. | n.a. | n.a. |
| LN (F) | <1 | <1 | n.a. | Ø | Ø | N |
| HM (M) | 0 | <1 | <1 | n.a. | n.a. | n.a. |
| OK (F) | 4 | <1 | <1 | Ø | Ø | N |
| MM (M) | <1 | <1 | <1 | ▾ | ▾ | (▾) |
| MU (F) | 82 | 57 | 42 | n | N | N |
| WC (M) | 0 | <1 | <1 | Ø | Ø | N |
| WV (F) | 68 | 35 | 25 | ▾ | ▾ | N |
| WA (M) | 78 | 66 | 22 | Ø | Ø | (▾) |
| PJ (M) | <1 | n.a. | n.a. | Ø | Ø | n |
N = Normal; Ø = absent; ▾ = inhibited or reduced; (▾) = slightly inhibited; n.a. = not analyzed.