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Anti-inflammatory cytokines. Levels (pg/mL) of IL-4 (a), IL-10 (b), and IL-13 (c) in supernatants of peritoneal leukocytes cultured under resting, LPS-, and ConA-stimulated conditions, from middle-aged, old, very old, and extreme long-lived female mice. Each column represents the mean ± standard error of 7–14 values, and each value is the mean of duplicate assays. ***p < 0.001, **p < 0.01, and *p < 0.05 with respect to the value in middle-aged animals
