Figure 2.

(a) Rigidity profile of GK when no mechanical stress is applied on the protein. (b) Variation of the force-constant profile upon applying an external constraint on the protein in pulling directions 75/171 (upper), 40/171 (middle), and 40/130 (lower). The black horizontal bars at the upper left of Fig. 2, a and b,indicate the position of the P-loop and the β7-sheet along the sequence.