Figure 4.

Distribution of the force-constant variation over all the pulling directions that have been modeled. Δk is expressed in kcal mol⁻¹ Å⁻². The black horizontal bars above the figure indicate the position of the P-loop and the β7-sheet along the sequence. The extended pairs have been ordered starting with the direction leading to the largest average perturbation, 〈abs(Δk)〉, of the GK rigidity profile. A negative/positive, value of Δk denotes a decrease/increase, of the rigidity of the residue.