. 2010 Nov 17;99(10):3412–3419. doi: 10.1016/j.bpj.2010.09.026

Table 1.

Overlap of constrained trajectories with relaxed trajectory along the 10 first modes of motions of the protein.

Pulling direction	Covariance matrix overlap (CMO)	Overlap of first eigenvectors
Thr⁷⁵-Arg¹⁷¹^∗	0.65	0.83
Cys⁴⁰-Arg¹⁷¹^∗	0.80	0.77
Cys⁴⁰-Lys¹³⁰^∗	0.83	0.97
Asp⁶⁵-Leu¹²²	0.66	0.55

^∗

Asterisks identify the pulling directions experimentally tested by Tseng et al. (48)