Table 1.
Default simulation parameters
Symbol | Parameter | Value | Units | Reference |
---|---|---|---|---|
NMT | Number of MTs | 50 | (8) | |
Naster | Number of astral MTs (per aster) | 15 | ||
Nfree | Number of free MTs | 20 | (32) | |
lfill | Length of free MTs | 5 | μm | (32) |
Rmem | Initial radius of the membrane | 4 | μm | |
kmem | Elastic modulus of membrane | 200–390 | pN/μm | (11) |
ηcyto | Viscosity of cytoplasm | 50×10−3 | pN μm2 | (8) |
ηmem | Viscosity of membrane | 10ηcyto | pN μm2 | estimate |
rgrid | Grid resolution | 187.5 | nm | |
rmotor | Motor capture radius | 10 | nm | (32) |
Dmotor | Motor diffusion coefficient | 0.04 | μm2/s | (8,13) |
FDynNL | No-load minus-end motor force | 0 | pN | |
FDynL | Loaded minus-end motor force | 4 | pN | (33) |
vDynNL | No-load minus-end motor velocity | 0.8 | μm/s | (33,34) |
vDynL | Loaded minus-end motor velocity | 0.2 | μm/s | (33) |
FKinNL | No-load plus-end motor force | 0 | pN | |
FKinL | Loaded plus-end motor force | 2 | pN | (13) |
vKinNL | No-load plus-end motor velocity | 0.08 | μm/s | (13) |
vKinL | Loaded plus-end motor velocity | 0.02 | μm/s | (13) |
kcon | Elastic modulus of motor connections | 20 | pN/ μm | |
rc | Interaction radius of membrane | 50 | nm | |
Δt | Time step | 100 | ms | (7,8) |