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. 2010 Nov 17;99(10):3473–3482. doi: 10.1016/j.bpj.2010.09.058

Figure 2.

Figure 2

NHERF1 alone can be described by a rigid-body model. (A) Three-dimensional shape of NHERF1 reconstructed from SAXS (14) using DAMMIN (28). For illustration, the structures of the PDZ1 (PDB code: 1I92) and PDZ2 (PDB code: 2KJD) are docked into the three-dimensional shape using UCSF Chimera software (31). EBD that interacts with PDZ2 is not marked. (B) Comparing experimental Deff(Q) of NHERF1 (open squares) with rigid-body calculation performed using dummy atoms (solid line). D0 (solid squares) is from PFG NMR (Table S1).