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Experimental IC50 values for SQ435 and Enfuvirtide against both wild-type HIV-1 and the N43D mutant
| Donor | IC50 SQ435 (mM) |
IC50 Enfuvirtide (nM) |
||
|---|---|---|---|---|
| Wild-type | N43D | Wild-type | N43D | |
| 140 | 29 | |||
| 187 | 253 | 172 | 14.0 | 122.9 |
| 188 | 109 | 46 | ||
| 189 | 6.1 | 234.6 | ||
| 190 | 229 | 176 | ||
| All data | 162 ± 28 | 112 ± 20 | 8.8 ± 1.3 | 167.8 ± 15.8 |
