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. 2010 Nov 17;99(10):3445–3453. doi: 10.1016/j.bpj.2010.09.050

Table 3.

Experimental IC50 values for SQ435 and Enfuvirtide against five clinical isolates of HIV-1 envelope

Envelope IC50 SQ435 (mM)
IC50 Enfuvirtide (nM)
Donor 195 Donor 196 All data Donor 195 Donor 196 All data
HXB2 193 156 174 4.3 14.4 7.5
SF162 198 167 180 48 75 63
YU-2 148 73 103 37 49 42
C98v1e4 237 199 215 64 59 62
C109v1e4 195 257 227 17 39 35
All env 188 ± 11 158 ± 15 172 ± 10 23 ± 5 66 ± 11 40 ± 6