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The effect of aging and CuAsp on left ventricular contractility. The slope (Ees) of the left ventricular ESPVR (A), PRSW (B), and dP/dtmax – EDV (C) are shown in young adult, young treated with CuAsp, aging, and aging treated with CuAsp rats. Values are mean ± SEM of six to eight experiments in each group. (*) p < 0.05 vs. young control; (#) p < 0.05 vs. aging control.
