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. 2010 Jun 9;31(22):2765–2773. doi: 10.1093/eurheartj/ehq167

Figure 5.

Figure 5

MicroRNAs plasma levels in mice with acute hind-limb ischaemia. miR-1, -133a, -133b, -499-5p, -122, and -375 plasma levels were evaluated in mice with acute hind-limb ischaemia, 6 and 24 h after femoral artery dissection. At 6 h, miR-1, -133a, and -133b exhibited a marked decrease, whereas miR-375 increased; all microRNAs were back to control value at 24 h. In contrast, miR-499-5p and miR-122 exhibited no significant change. (n = 5 for hind-limb ischaemia and n = 5 for sham operated; values indicate fold changes of each microRNA vs. sham-operated mice; results for each microRNA are reported as mean ± SEM; NS, not significant; §P < 0.05). Control values were arbitrarily set to 1 as indicated by the red bar.