Table 4.
Correlation of rCBF responses to 2-back working memory task among pre-frontal, parietal, and amygdala/hippocampal ROI’s.
| Correlation | Pre-Treatment N=28 |
Post-Treatment N=28 |
Significance Of Difference |
|---|---|---|---|
| Pre-Frontal to Parietal | .62* | .94* | P=.006 |
| Pre-Frontal to Amygdala/Hippocampus | .58* | .84* | P=.05 |
| Parietal to Amygdala/Hippocampus | .42* | .80* | P=.03 |
p< or =.01. Pre-treatment correlations show a similar pattern when participants with PET data only for the pre-treatment are added to the calculation (to yield n=43) and the significance of the pre-frontal to parietal correlation difference remains (p=.002). Removal of one participant with extreme change scores reduces the amygdala/hippocampus differences to a trend but the difference between prefrontal/parietal correlations pre and post remains significant (p=.04).