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Number and frequencies of APOL1 genotypes and alleles in FSGS and hypertension-attributed ESKD cases and controls.
| Genotype | BWH FSGS Cases | NIH FSGS Cases | Total Cases | Controls | H-ESKD Cases | Controls |
|---|---|---|---|---|---|---|
| WT+WT | 3 | 26 | 29 | 77 | 239 | 409 |
| WT+G1 | 6 | 21 | 27 | 41 | 173 | 250 |
| WT+G2 | 0 | 9 | 9 | 36 | 124 | 155 |
| G1+G1 | 25 | 35 | 60 | 9 | 219 | 41 |
| G1+G2 | 15 | 38 | 53 | 8 | 203 | 50 |
| G2+G2 | 3 | 11 | 14 | 5 | 44 | 18 |
| Total | 52 | 140 | 192 | 176 | 1002 | 923 |
| Allele | ||||||
| G1 Freq. | 0.68 | 0.47 | 0.52 | 0.18 | 0.41 | 0.21 |
| G2 Freq. | 0.19 | 0.25 | 0.23 | 0.15 | 0.21 | 0.13 |
