Table 4.
Retrospective and Prospective Cohort Neurocognitive Test Scores
| Retrospective Cohort (N=24)a | Prospective Cohort (N=15) | |||
|---|---|---|---|---|
| Cognitive Domain | Test Score, (IQR) | % of Children with Score > 1.5 SD below norms | Test Score, (IQR) | % of Children with Score >1.5 SD below norms |
| Intelligence | ||||
| Full Scale IQ | 93.5 (83.8-101.0) | 12.5 | 99.0 (94.0-109.0) | NONE |
| Attention | ||||
| Trails A | 102.0 (83.3-109.8) | 13.6 | 105.0 (88.0-117.0) | 13.3 |
| CCPT b | ||||
| Omissions | 99.5 (93.0-108.0) | 9.1 | NA | |
| Commissions | 105.0 (90.0-124.0) | 4.4 | NA | |
| Executive Functioning | ||||
| Trails B | 92.5 (40.0-108.2) | 31.8 | 95.0 (81.0-106.0) | 20.0 |
| Verbal Fluency | 86.0 (75.5-91.0) | 28.6 | 72.0 (65.0-103.0) | 53.3 |
| WCSTb | 94.5 (82.5-111.8) | NONE | NA | |
| Visuo-spatial Functioning | ||||
| RCFT-copyc | NA | 25 | NA | 20 |
| VMI | 86.0 (74.0-97.0) | 38.1 | 76.0 (64.0-84.0) | 53.3 |
| Psychomotor Speed | ||||
| Grooved Pegboard | ||||
| Dominant | 90.5 (63.8-103.8) | 40.9 | 101.0 (90.0-110.0) | 20.0 |
| Non-dominant | 88.0 (68.0-106.0) | 34.8 | 95.0 (79.0-110.0) | 13.3 |
| Finger Tappingb | ||||
| Dominant | 93.0 (82.3-112.3) | 16.7 | NA | |
| Non-dominant | 95.5 (81.5-107.8) | 16.7 | NA | |
| Memory | ||||
| RCFT-recall | ||||
| Immediate | 72.0 (58.7-85.0) | 61.1 | 95.0 (79.0-109.0) | 26.7 |
| Delayed | 72.0 (57.0-81.0) | 64.7 | 84.0 (73.0-114.0) | 26.7 |
| TOMALb | ||||
| Word Reminding | ||||
| Immediate | 90.0 (85.0-102.5) | 9.5 | NA | |
| Delayed | 105.0 (95.0-110.0) | 9.5 | NA | |
a
Some patients in the Retrospective cohort did not complete all tests (Finger tapping N=12, RCFT N=18, WCST N=15)
b
CCPT, WCST and TOMAL tests were not part of the prospective cohort neuropsychology protocol.
c
RCFT copy scale is reported as a percentile score (score of < 77.5 = < 6%)