Table 2.
Variablea | Nulliparous (N = 718) | Normotensive pregnancy (N = 3421) | Hypertensive pregnancy (N = 643) | Normotensive vs. nulliparous P value | Hypertensive vs. normotensive P value |
---|---|---|---|---|---|
History of smokingb | 24.7 | 31.5 | 29.6 | <0.001 | 0.336 |
BMIc | 27.94 | 28.50 | 31.19 | – | – |
Log BMId | 3.33 ± 0.25 | 3.35± 0.20 | 3.44± 0.21 | 0.028 | <0.001 |
Diabetese | 21.1 | 18.0 | 25.5 | 0.037 | <0.001 |
Dyslipidemiaf | 81.9 | 77.0 | 72.0 | 0.193 | 0.069 |
Family history of stroke | 23.0 | 24.7 | 29.6 | 0.281 | 0.004 |
Family history of CHD | 30.2 | 33.7 | 38.6 | 0.041 | 0.004 |
Current HTNg | 49.3 | 39.8 | 57.6 | <0.001 | <0.001 |
Family history of HTN | 67.8 | 72.3 | 79.8 | 0.018 | <0.001 |
CHD, coronary heart disease; GENOA, Genetic Epidemiology Network of Arteriopathy; HTN, hypertension.
All variables were adjusted for age, network, and race and expressed as percentages, with the exception of BMI, which was expressed as a mean. P values are calculated from a generalized linear regression model using generalized estimating equations to account for sibling relationships.
Two normotensive patients missing smoking history.
Two nulliparous, 11 normotensive, and one hypertensive patient missing BMI data.
Due to skewness of distribution, log BMI (mean ± SD) was used for comparison between the groups.
Two nulliparous and five normotensive patients missing diabetes data.
GENOA participants only, N = 149, 1303, and 293, respectively.
Two normotensive and two hypertensive patients missing current hypertension status.