TABLE 2.
Inflammation indexes | Day 1 (before treatment) | Day 25 (after treatment) | P |
Parasites (no./μL) | 880 (123–2760) | 0 (0) | 0.0012 |
C-reactive protein (mg/dL) | 0.9 (0.4–5.7) | 0.30 (0.3–0.4) | 0.0012 |
Hepcidin (nmol/L) | 2.7 (1.0–4.6) | 1.4 (0.7–2.4) | 0.0052 |
GDF-15 (pg/mL) | 497 (400–612) | 381 (341–432) | 0.0032 |
Interleukin-6 (pg/mL) | 1.32 (0.96–1.92) | 1.27 (0.70–1.32) | 0.0312 |
Interleukin-8 (pg/mL) | 7.31 (4.58–10.03) | 4.18 (2.60–5.67) | 0.0013 |
Interleukin-10 (pg/mL) | 7.38 (4.44–13.93) | 2.94 (1.91–2.94) | 0.0013 |
All values are medians; 25th–75th percentiles in parentheses. GDF-15, growth differentiation factor 15.
Wilcoxon's signed-rank test (log transformed).
Paired t test (log transformed).