TABLE 5.
Hazard ratios (HRs) and population attributable risk (PAR) of fatty acid (FA) intake and fracture risk factors1
| Fracture type and exposure | Prevalence | HR (95% CI) | PAR2 (95% CI) |
| Hip fractures | |||
| Highest (Q4) SFA intake | 0.25 | 1.235 (1.108, 1.375) | 0.055 (0.026, 0.086) |
| Lowest (Q1) body weight | 0.25 | 1.361 (1.228, 1.508) | 0.083 (0.054, 0.113) |
| Parental history of fracture | 0.39 | 1.197 (1.081, 1.325) | 0.073 (0.031, 0.115) |
| Current smoking | 0.0695 | 1.849 (1.547, 2.209) | 0.056 (0.037, 0.077) |
| Current corticosteroid use | 0.0095 | 2.583 (1.908, 3.497) | 0.015 (0.009, 0.023) |
| Total fractures | |||
| Lowest (Q1) MUFA intake | 0.25 | 1.056 (1.024, 1.089) | 0.014 (0.006, 0.022) |
| Lowest (Q1) PUFA intake | 0.25 | 1.045 (1.013, 1.078) | 0.011 (0.003, 0.019) |
| Lowest (Q1) n−6 FA intake | 0.25 | 1.055 (1.023, 1.089) | 0.014 (0.006, 0.022) |
| Lowest (Q1) body weight | 0.25 | 0.999 (0.967, 1.031) | 0.000 (−0.008, 0.008) |
| Parental history of fracture | 0.399 | 1.220 (1.185, 1.255) | 0.081 (0.069, 0.093) |
| Current smoking | 0.0695 | 1.110 (1.051, 1.173) | 0.008 (0.003, 0.012) |
| Current corticosteroid use | 0.0095 | 1.744 (1.557, 1.953) | 0.007 (0.005, 0.009) |
1
Q, quartile; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid. HRs and 95% CIs were obtained from Cox proportional hazard models. All models were adjusted for age and ethnicity.
2
Calculated as follows: prevalence × (HR − 1)/1 + prevalence × (HR − 1).