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. 2010 Oct 13;92(6):1461–1467. doi: 10.3945/ajcn.110.000026

TABLE 3.

Association between adherence to the alternate Mediterranean Diet Score (aMED) and adjusted geometric mean concentrations of plasma lipid peroxidation and serum antioxidants1

Outcome and model Difference per 1-unit increase in aMED 95% CI Mean aMED2
 P value3
0–2 2.01–3 3.01–4 4.01–9
%
No. of cycles — — 128 187 126 68 —
Lipid peroxidation
 8-iso-PGF2α (pg/mL)
 Energy adjusted −4.48 (−6.35, −2.58) 50.57 48.67 46.61 45.06 0.01
 Fully adjusted4 −4.50 (−6.32, −2.65) 54.49 52.33 49.98 48.85 0.003
 9-HODE (μmol/L)
 Energy adjusted −13.45 (−17.21, −9.53) 0.19 0.16 0.13 0.11 0.05
 Fully adjusted4 −14.01 (−17.88, −9.96) 0.19 0.15 0.13 0.12 <0.001
 TBARS (nmol/mL)
 Energy adjusted 0.87 (−0.21, 1.96) 0.84 0.84 0.83 0.88 0.19
 Fully adjusted4 1.01 (−0.10, 2.22) 0.83 0.83 0.82 0.86 0.12
Antioxidants
 α-Tocopherol (μg/mL)
 Energy adjusted −0.04 (−0.90, 0.83) 8.00 7.91 8.06 7.97 0.69
 Fully adjusted5 0.16 (−0.67, 0.99) 8.25 8.19 8.33 8.24 0.75
 δ-Tocopherol (μg/mL)
 Energy adjusted 0.64 (−0.35, 1.64) 0.17 0.17 0.18 0.19 0.48
 Fully adjusted5 0.64 (−0.41, 1.64) 0.15 0.15 0.16 0.17 0.39
 γ-Tocopherol (μg/mL)
 Energy adjusted −1.39 (−3.04, 0.32) 1.67 1.67 1.66 1.60 0.27
 Fully adjusted5 −1.29 (−2.75, 0.67) 1.65 1.65 1.64 1.59 0.44
 Retinol (μg/mL)
 Energy adjusted −0.12 (−0.98, 0.76) 0.37 0.37 0.37 0.37 0.60
 Fully adjusted5 −0.08 (−0.94, 0.79) 0.38 0.38 0.38 0.38 0.89
 Ascorbic acid6 (mg/dL)
 Energy adjusted 1.44 (0.14, 2.77) 1.69 1.67 1.73 1.73 0.04
 Fully adjusted5 1.39 (0.07, 2.72) 1.67 1.65 1.71 1.70 0.07
1

8-iso-PGF2α, F2-isoprostane; 9-HODE, 9-hydroxyoctadecadieneoic acid; TBARS, thiobarbituric acid reactive substances. Analyses used linear mixed models with random intercepts.

2

Values are geometric means.

3

P values were calculated by using a test for trend across aMED category.

4

Adjusted for energy intake (kcal, continuous), age (continuous), race (white, black, other), BMI (continuous), plasma ascorbic acid (continuous), and serum cholesterol (continuous).

5

Adjusted for energy intake (kcal, continuous), age (continuous), race (white, black, other), BMI (continuous), and serum cholesterol (continuous).

6

Ascorbic acid was measured in plasma.