TABLE 1.
Physical and metabolic characteristics of subjects by genotype (n = 153)1
| CC (n = 38) | CG (n = 70) | GG (n = 45) | P value2 | |
| Sex (n) | 0.42 | |||
| Male | 6 | 22 | 11 | |
| Female | 32 | 48 | 34 | |
| Age (y) | 13.3 ± 3.03 | 14.1 ± 2.9 | 14.0 ± 2.9 | 0.32 |
| Weight (kg) | 75.9 ± 33.8 | 77.9 ± 28.7 | 81.5 ± 31.8 | 0.74 |
| BMI (kg/m2) | 30.7 ± 8.6 | 31.4 ± 7.5 | 32.5 ± 8.6 | 0.61 |
| BMI percentile | 91.7 ± 14.7 | 94.7 ± 9.4 | 95.7 ± 6.4 | 0.50 |
| BMI z score | 1.8 ± 0.8 | 2.0 ± 0.6 | 2.0 ± 0.6 | 0.22 |
| Total fat mass (kg) | 30.3 ± 15.1 | 30.4 ± 11.6 | 31.8 ± 14.9 | 0.87 |
| Total lean mass (kg)4 | 45.0 ± 15.1 | 44.7 ± 14.7 | 45.5 ± 15.3 | 0.98 |
| VAT (L) | 1.6 ± 1.0 | 1.7 ± 1.3 | 1.8 ± 1.0 | 0.89 |
| SAAT (L) | 9.1 ± 5.2 | 10.0 ± 6.2 | 10.3 ± 6.8 | 0.63 |
| Hepatic fat (%) | 4.5 ± 4.1a | 5.9 ± 5.8a | 9.7 ± 8.10b | <0.001 |
1
VAT, visceral adipose tissue; SAAT, subcutaneous abdominal adipose tissue. Values with different superscript letters are significantly different, P < 0.001 (Bonferroni multiple comparisons).
2
ANOVAs with Bonferonni adjustments and chi-square tests (for sex only) were used to determine significant differences between genotype groups. The P values represent the overall significance between genotype groups.
3
Mean ± SD (all such values).
4
Does not include bone mineral content.