Figure 4.
A, Kaplan-Meier survival curve of neu-N mice treated with 120 μCi μCi 213Bi-7.16.4 (n = 14). Inoculation of metastases was induced by left cardiac injection of 1 × 104 NT2.5 cells. B, Kaplan-Meier survival curve of neu-N mice with two courses of treatments after LCV inoculation of NT2.5 cells. Neu-N mice were initially treated with 120 μCi 213Bi-7.16.4, and 10 d later they were treated again with either 120 μCi (n = 10), 90 μCi (n = 8) 213Bi-7.16.4, or 4 mg/kg unlabeled 7.16.4 (n = 8).