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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Pediatr Cardiol. 2009 Dec 5;31(3):335–341. doi: 10.1007/s00246-009-9605-0

Fig. 1.

Fig. 1

General domain structure of the cardiac NK-2 family of proteins. Four conserved motifs are found consistently in the NK-2 family of proteins. The domains and the amino acid sequence from human NKX2–5 corresponding to each domain starting from the amino terminus of the protein are the TN domain, the homeodomain, the NK-2 domain, and the sequence GIRAW. One of the distinguishing features of the homeodomain is the presence of a tyrosine (Y) at amino acid position 54