Fig. 2.

The cardiac NK-2 factors can be sorted into three syntenic groups. Using the program Metazome (http://www.metazome.net/) and the genomic database at the Joint Genome Institute, a search for all chordate NK-2 genes was conducted, and a syntenic cluster analysis was performed. In each case, the cardiac NK-2 gene is indicated in black. Genes with a common identity are color coded, and the non-matching sequence is in white. Clustering based on NKX2–3, NKX2–5, and NKX 2–6 for human (Hsa), mouse (Mmu), rat (Rno), opossum (Mdo), chicken (Gga), frog (Xtr), and zebra fish (Dre) are included in the analysis