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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: J Am Chem Soc. 2008 Jan 31;130(8):2416–2417. doi: 10.1021/ja710521m

Table 3.

Aldehyde Reaction Scope

graphic file with name nihms248683u3.jpg
entry R yielda (%) eeb (%)
1 4-Cl–C6H4 78 (11) 90
2 4-MeO–C6H4 72 (12) 89
3 2-naphthyl 73 (13) 94
4 Mec 73 (14) 94
5 C3H7c 64 (15) 92
a

Isolated yields.

b

Enantiomeric excess determined by HPLC Chiracel OD-H or AD-H.

c

DBU used in place of Et3N.