Binary logistic regression analysis was performed for all patients and for patients stratified by primary histology. A trend towards significance was observed for patients with non-small-cell lung cancer (NSCLC) (p=0.109) and melanoma (p=0.067). Statistical significance was observed for all patients (p=0.003) and for patients with small cell lung cancer (SCLC) (p=0.027) and malignancies other than NSCLC, SCLC, melanoma, breast cancer, or renal cell cancer (p=0.033). Patients with renal cell carcinoma were not included in this figure, as none of them had a metastasis within 5 mm of the hippocampus. Patients with breast cancer were not included in this figure, as statistical significance was not observed. Abbreviations: NSCLC, non-small-cell lung cancer, SCLC, small cell lung cancer