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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Mol Microbiol. 2010 Aug 16;77(6):1595–1605. doi: 10.1111/j.1365-2958.2010.07310.x

Figure 5.

Figure 5

Proper regulation of the Pho regulon is required during V. cholerae infection. Competition assays were performed using the infant mouse model of infection. All strains were competed against wild-type O395. The competitive index is the ratio of mutant to wild-type bacteria recovered from the small intestine corrected for the input ratio. Each data point represents the competitive index from an individual mouse; the gray bar represents the geometric mean. The ΔphoB, Δpst, ΔphoB Δpst and ΔphoR strains are significantly attenuated (P<0.01) by Student’s two-tailed t-test.