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. Author manuscript; available in PMC: 2011 Mar 17.
Published in final edited form as: Circ Res. 2010 Jul 29;107(6):10.1161/CIRCRESAHA.109.216127. doi: 10.1161/CIRCRESAHA.109.216127

Figure 3. Cav1.2 function and AKAP5.

Figure 3

A, Whole cell patch clamp recording of ICa as a function of voltage in WT (left panel) and KO (right panel) cardiomyocytes before and after stimulation by isoproterenol (100 nmol/L) (n=12 cells from 3 animals). B, Whole cell patch clamp recording of ICa as a function of voltage in WT (left panel) and KO (right panel) cardiomyocytes before and after stimulation with forskolin (Fsk, 10 umol/L) (n=10 cells from 3 animals). C, The fold change of the stimulated ICa measured at 10 mV for isoproterenol (Iso, 100 nmol/L) or forskolin (Fsk, 10 umol/L) (mean ± s.e.m., n=3 animals;**P<0.001)