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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: Synthesis (Stuttg). 2009;4:687–690. doi: 10.1055/s-0028-1083284

Table 1.

Reaction Optimization

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Entry Temp (°C) Basea Azolium salt Yieldb (%) eec (%)
1 23 DBU A 0 –
2 23 i-Pr2EtN A 47 −83
3 23 i-Pr2EtN B 38 −76
4 23 i-Pr2EtN C 45 51
5 23 i-Pr2EtN D 40 94
6d 23 i-Pr2EtN D 66 94
7d 40 i-Pr2EtN D 80 93
8d,e 40 i-Pr2EtN D 70 93
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a

1 equiv of base used.

b

Isolated yields.

c

Determined by HPLC (Chiralcel OD-H).

d

Careful exclusion of oxygen.

e

5 mol% of D.