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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: Free Radic Biol Med. 2007 Jul 10;43(7):1023–1036. doi: 10.1016/j.freeradbiomed.2007.06.027

Fig. 1.

Fig. 1

Conrad Waddington’s depiction of an epigenetic landscape during development. “A symbolic representation of the developmental potentialities of a genotype in terms of a surface, sloping towards the observer, down which there run balls each of which has a bias corresponding to the particular initial conditions in some part of the newly fertilised egg. The sloping surface is grooved, and the balls will run into one or other of these channels, finishing at a point corresponding to some typical organ”. Figure and legend from Waddington, 1956 [20].