TABLE 2.
Infection route | Inoculum (CFU) | Genotype of straina: |
Median CIb | P valuec | No. of mice | |
---|---|---|---|---|---|---|
A | B | |||||
i.p.d | 103 | ΔfliZ | WT | 1.08 | NS | 9 |
Orale | 107 | ΔfliZ | WT | 0.016 | <0.005 | 11 |
109 | ΔfliZ Δspi1 | Δspi1 | 0.2 | <0.005 | 16 |
The strains used were JS135, JS990, JS481, and JS991.
The competitive index (CI) was calculated as described in Materials and Methods.
The Student t test was used to compare the CIs to the inocula. NS, not significant.
Bacteria were recovered from the spleen in the case of intraperitoneal (i.p.) competition assays.
Bacteria were recovered from the distal portion of the small intestine in oral competition assays.