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. 2010 Sep 20;54(12):4971–4977. doi: 10.1128/AAC.00834-10

TABLE 3.

Mutations identified in the lipid A biosynthesis genes of colistin-resistant A. baumannii ATCC 19606 derivatives

Strain Gene Nucleotide change Effect
AL1833 lpxC C → T substitution at nt 89 Amino acid change P30L
AL1834 lpxC Single base deletion at nt 135 Frameshift after D45
AL1842 lpxC 84-bp deletion at nt 858 Frameshift after T285
AL1843 lpxC C → T substitution at nt 89 Amino acid change P30L
AL1844 lpxA C → G substitution at nt 475 Amino acid change H159D
AL1845 lpxA C → T substitution at nt 700 Truncation after D233
AL1846 lpxA G → A substitution at nt 203 Amino acid change G68D
AL1847 lpxA 30-bp deletion at nt 391 Frameshift after D130
AL1848 lpxA C → A substitution at nt 214 Amino acid change Q72K
AL1849 lpxA 2-bp deletion at nt 76 Frameshift after I25
AL1851 lpxA 445-bp deletion at nt 364 Frameshift after H121
AL1852 lpxD Single base deletion at nt 952 Frameshift after K317