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. 2010 Sep 27;54(12):5257–5268. doi: 10.1128/AAC.00515-10

FIG. 5.

FIG. 5.

Comparisons of time-of-addition profiles of three novel anti-HIV molecules from a natural product collection with those of selected reference anti-HIV drugs. (A) Comparison of the profiles of abyssinone IV and the reference drugs AZT and RAL. (B) Comparison of the profiles of 3,12-dioxocholanic acid (3,12-DCA) and the reference drugs RAL and DRV. (C) Comparison of the profiles of 7-alpha-acetoxy-6-beta-hydroxyroyleanone (ROY) and the reference drug DRV. Data for profiles of reference anti-HIV drugs were taken from Fig. 4. Solid line, analysis of HIV reporter expression in test cultures; dotted line, analysis of amounts of infectious virus in supernatants of test cultures. Each data point represents the mean of values measured in at least three wells for a single time point.