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. 2010 Oct 4;78(12):5341–5351. doi: 10.1128/IAI.00845-10

FIG. 1.

FIG. 1.

IL-17A depletion in mice infected with C. neoformans strain H99γ. BALB/c mice received an intranasal inoculation with C. neoformans strain H99γ and were treated with IL-17A antibody or isotype control IgG2a antibody. The lungs from each group of mice were excised at days 7 and 14 postinoculation and assayed for IL-17A cytokine expression. Data represent cumulative results from four experiments utilizing five mice per group. Asterisks indicate where significant decreases in IL-17A levels (**, P < 0.001; *, P < 0.05) were observed in IL-17A-depleted mice compared to the levels in isotype control-treated mice following infection with C. neoformans strain H99γ.