FIG. 6.

The depletion of IL-17A during pulmonary infection with C. neoformans strain H99γ does not alter the pulmonary cytokine environment. BALB/c mice received an intranasal inoculation with C. neoformans strain H99γ and were treated with IL-17A antibody or isotype control IgG2a antibody. Lung homogenates were prepared from lungs excised on days 7 and 14 postinoculation and assayed for IL-2, IL-4, IL-5, IL-12, IL-13, and IFN-γ cytokine production. Data represent cumulative results from three experiments utilizing five mice per group.