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. 2010 Oct 4;78(12):5341–5351. doi: 10.1128/IAI.00845-10

FIG. 7.

FIG. 7.

IL-17RA−/− mice have similar pulmonary F4/80 and iNOS expression during experimental pulmonary infection with C. neoformans strain H99γ compared to expression in wild-type mice. IL-17RA−/− and wild-type BALB/c mice received an intranasal inoculation with C. neoformans strain H99γ. Lungs were excised on day 7 postinoculation and immediately frozen in OCT medium. Lungs were cryosectioned and expression of F4/80 and iNOS was evaluated using immunofluorescence staining with anti-F4/80 or anti-iNOS antibodies. Nuclei were counterstained with DAPI. Data shown are representative lung sections from two independent experiments (three mice per group). Digital photographs show representative areas of lungs (20× objective).