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(A and B) Opsonophagocytic killing of clinical pneumococcal isolates (A) and pneumococcal reference strains (B). Each strain was analyzed with three different serum pools from children immunized with a pneumococcal conjugate vaccine and the results are presented as the geometric mean anticapsular antibody concentration (GMC) required for 50% opsonophagocytic killing with 95% confidence intervals. The number of clinical isolates analyzed per serotype is shown in parentheses.
