TABLE 3.
Serum antibody concentrations to capsular polysaccharides in pooled sera used in the opsonophagocytic assay
| Serotype | Geometric mean IgG concn in μg/ml in pooled sera (95% CI)a |
||
|---|---|---|---|
| Low | Medium | High | |
| 1 | 5.9 (3.2-11) | 6.6 (5.3-8.1) | 14 (11-20) |
| 4 | 1.4 (0.8-2.5) | 6.2 (3.4-11) | 15 (11-20) |
| 5 | 1.7 (1.0-2.8) | 6.4 (4.6-9.0) | 13 (8.5-20) |
| 6B | 1.2 (0.9-1.5) | 5.8 (4.9-7.0) | 15 (11-20) |
| 14 | 1.3 (0.7-2.4) | 5.8 (3.4-9.8) | 10 (5.2-19) |
| 18C | 1.2 (0.8-1.8) | 4.3 (2.5-7.5) | 16 (10-26) |
| 19F | 5.2 (5.0-5.4) | 7.2 (6.6-7.9) | 16 (14-17) |
| 23F | 1.3 (0.7-2.4) | 5.8 (3.4-9.8) | 10 (5.2-19) |
a
That is, the geometric mean IgG concentrations in pooled sera from infants immunized with an 11-valent pneumococcal conjugate vaccine. The 95% confidence intervals (95% CI) are given in parentheses. Each pool was collected from 5 to 11 different sera.