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MyD88−/−, TLR2−/−, and TLR4−/− mice are resistant to Parachlamydia infection. Survival (A and C) and P. acanthamoebae genomic copy number in the lungs (day 8) (B) of mice infected with 2.5 × 108 (A and B) and 1.25 × 108 (C) P. acanthamoebae bacteria is shown (n = 25 or 26 mice per group for panel A and n = 6 to 8 mice per group for panel C); P > 0.05 for all conditions.
