Neuro-endocrine regulation of male and female reproduction in Lymnaea stagnalis. (A) Schematic drawing of the involved ganglia of the central nervous system. The blue and red areas show, respectively, the neuronal clusters that are involved in male and female reproduction. The substances involved in male reproduction are also indicated in blue; the female ones are listed in red. com, cerebral commissure; icn, inferior cervical nerve; ni, nervus intestinalis; np, nervus penis; RN, ring neuron; RPeN, right pedal neurons; st statocyst. This figure is adapted from Jarne et al. (2010). (B) Overview of the identified neuropeptides and proteins involved in reproduction. SS stands for signal sequence, numbered Cs stand for different connecting peptides, all the other peptides can be found in (A) of the figure. See text and Table 1 for further details and references.