Table 5.
Down-regulated genes observed in at least two datasets*
| Genes | Description | Datasets |
|---|---|---|
| CASQ2 | calsequestrin 2 (cardiac muscle) | humani, human2 |
| DES | desmin | humani, human2 |
| DMD | dystrophin (muscular dystrophy, Duchenne and Becker types) | humani, human2 |
| DMN | desmuslin | humani, human2 |
| FHL1 | four and a half LIM domains 1 | humani, human2 |
| FOXF1 | forkhead box F1 | humani, human2 |
| KIAA0367 | KIAA0367 | humani, human2 |
| LMOD1 | leiomodin 1 (smooth muscle) | humani, human2 |
| PLN | phospholamban | humani, human2 |
| PTGIS | prostaglandin 12 (prostacyclin) synthase | humani, human2 |
| REEP1 | receptor accessory protein 1 | humani, human2 |
| SORBS1 | sorbin and SH3 domain containing 1 | humani, human2 |
| TNS1 | tensin 1 | humani, human2 |
| TPM2 | tropomyosin 2 (beta) | humani, human2 |
| CNN1 | calponin 1, basic, smooth muscle | humani, human2, mouse |
| MYL9 | myosin, light chain 9, regulatory | humani, human2, mouse |
| PDLIM3 | PDZ and LIM domain 3 | humani, human2, mouse |
| ITIH5 | inter-alpha (globulin) inhibitor H5 | humani, mouse |
| MYH11 | myosin, heavy chain 11, smooth muscle | human2, mouse |
| PCP4 | Purkinje cell protein 4 | human2, mouse |
| FMO5 | flavin containing monooxygenase 5 | rat1, mouse |
| ACE2 | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 | rat1, rat2 |
| AHRR | aryl-hydrocarbon receptor repressor | rat1, rat2 |
| CAPN13 | calpain 13 | rat1, rat2 |
| CASKIN1 | CASK interacting protein 1 | rat1, rat2 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | rat1, rat2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | rat1, rat2 |
| CYP3A18 | cytochrome P450, family 3, subfamily A, polypeptide 18 | rat1, rat2 |
| DPYD | dihydropyrimidine dehydrogenase | rat1, rat2 |
| EGFL6 | EGF-like-domain, multiple 6 | rat1, rat2 |
| FNDC5 | fibronectin type III domain containing 5 | rat1, rat2 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | rat1, rat2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4 | rat1, rat2 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | rat1, rat2 |
| PAK3 | p21 (CDKNIA)-activated kinase 3 | rat1, rat2 |
| PCBP3 | poly(rC) binding protein 3 | rat1, rat2 |
| PLAG1 | pleiomorphic adenoma gene 1 | rat1, rat2 |
| PLCE1 | phospholipase C, epsilon 1 | rat1, rat2 |
| PRKCQ | protein kinase C, theta | rat1, rat2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | rat1, rat2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | rat1, rat2 |
| SLC15A2 | solute carrier family 15 (H+/peptide transporter), member 2 | rat1, rat2 |
| SLC23A1 | solute carrier family 23 (nucleobase transporters), member 1 | rat1, rat2 |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 | rat1, rat2 |
| TSHR | thyroid stimulating hormone receptor | rat1, rat2 |
| KRT20 | keratin 20 | rat1, rat2, mouse |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | rat1, rat2, mouse |
| SH3GL2 | SH3-domain GRB2-like 2 | rat1, rat2, mouse |
| SLC16A7 | solute carrier family 16, member 7 (monocarboxylic acid transporter 2) | rat1, rat2, mouse |
| FLJ45455 (RGD1564618) | FLJ45455 protein (similar to novel protein) | rat2, human2 |
| HIP1R | huntingtin interacting protein 1 related | rat2, mouse |
| NDRG2 | NDRG family member 2 | rat2, mouse |
| UPK2 | uroplakin 2 | rat2, mouse |
| MFSD4 | major facilitator superfamily domain containing 4 | rat2, mouse |
*
The DEGs were defined as genes with Q value < 0.01, LFDR < 0.05 and fold change > 1.5 between two groups; the top 100 DEGs in each dataset were compared.