Table 1.

Baseline Echocardiographic Parameters in Wild-Type and Ames Dwarf Mice

	Wild Type (N = 7)	Dwarf (N = 8)
Age (mo)	11.9 ± 0.2	11.8 ± 0.1
Heart rate (beats/min)	420 ± 5	385 ± 16
Tibia (mm)	16.6 ± 0.3	12.2 ± 0.7*
End-diastolic dimensions/tibia (mm/mm)	0.25 ± 0.01	0.26 ± 0.02
End-systolic dimensions/tibia (mm/mm)	0.16 ± 0.01	0.17 ± 0.01
Fractional shortening (%)	36 ± 2	35 ± 2
Diastolic wall thickness/tibia (mm/mm)	0.054 ± 0.002	0.045 ± 0.005
Systolic wall thickness/tibia (mm/mm)	0.078 ± 0.004	0.068 ± 0.006

Note: Physiological parameters of cardiac function were measured in eight wild-type and seven Ames dwarf mice. Data are shown as M ± SEM. *p < .05 vs wild type.