Table 2.

Association of EBV serostatus and category of EBV antibody titer with risk of all NHL

Exposure	Cases, n	Controls, n	Simple RR (95% CI)*
EBV serostatus
Positive	319	629	Ref
Negative	21	33	1.22 (0.71-2.12)
Anti–EBNA-1, titer†
< 320	252	505	Ref
≥ 320	67	124	1.07 (0.76-1.52)
Anti–EBNA-2, titer†
< 80	256	512	Ref
≥ 80	63	117	1.06 (0.74-1.52)
Anti-VCA, titer†
< 10 240	275	553	Ref
≥ 10 240	44	76	1.27 (0.84-1.93)
Anti-EA, titer†
< 640	268	525	Ref
≥ 640	51	104	0.97 (0.66-1.42)
EBNA-1/EBNA-2 ratio†
> 1.0	210	424	Ref
≤ 1.0	109	205	1.07 (0.79-1.44)

EBV indicates Epstein-Barr virus; NHL, non-Hodgkin lymphoma; EBNA, Epstein-Barr nuclear antigen; VCA, viral capsid antigen; EA, early antigen; RR, rate ratio; and CI, confidence interval.

^*Conditional logistic regression models adjusting for the matching factors (sex/study, age, race, month and year of blood draw, fasting status).

^†Among EBV-seropositive subjects only.