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. 2010 Oct 8;45(6):495–500. doi: 10.1093/alcalc/agq066

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© The Author 2010. Published by Oxford University Press on behalf of the Medical Council on Alcohol.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Atrogin-1 and MuRF-1 gene expressions in rat plantaris. Real-time PCR analyses were performed for atrogin-1 and MuRF-1in plantaris muscles from rats chronically fed alcohol (EtOH) for 12 weeks. Alcohol ingestion dramatically increased mRNA levels of both E3 ligases. Two weeks of ABS was sufficient to normalize atrogin-1 and MuRF-1 inductions due to alcohol ingestion with no additional benefits conferred by PRO supplementation. Data are represented as means ± range of potential values based on the method (Otis et al., 2007; Otis et al., 2008) and expressed as fold changes relative to controls (n = 6–7 rats/group). Significance was accepted at P ≤ 0.05. *, compared with control group. #, compared with EtOH group.

Inline graphic — Atrogin-1 and MuRF-1 gene expressions in rat plantaris. Real-time PCR analyses were performed for atrogin-1 and MuRF-1in plantaris muscles from rats chronically fed alcohol (EtOH) for 12 weeks. Alcohol ingestion dramatically increased mRNA levels of both E3 ligases. Two weeks of ABS was sufficient to normalize atrogin-1 and MuRF-1 inductions due to alcohol ingestion with no additional benefits conferred by PRO supplementation. Data are represented as means ± range of potential values based on the method (Otis et al., 2007; Otis et al., 2008) and expressed as fold changes relative to controls (n = 6–7 rats/group). Significance was accepted at P ≤ 0.05. *, compared with control group. #, compared with EtOH group.