Table 3. Correlations of serum uridine levels with metabolic, infectious and treatment factors.
Serum uridine (µmol/l) | Serum uridine (BMI-adjusted) | |||
r | P | r | P | |
BMI | 0.1280 | 0.0465 | ||
Age | 0.0140 | 0.8205 | −0.0040 | 0.9470 |
Waist circumference | 0.0970 | 0.1218 | 0.0350 | 0.5890 |
WHR | −0.0010 | 0.9868 | −0.0440 | 0.4920 |
Fat percentage | 0.1630 | 0.0093 | 0.1250 | 0.0520 |
Trunk/apendicular fat ratio | − 0.0630 | 0.3126 | -0.0690 | 0.2830 |
Fasting glucose | −0.0820 | 0.1950 | -0.0990 | 0.1260 |
Fasting insulin | 0.0420 | 0.5092 | −0.0650 | 0.3170 |
HOMA-IR | −0.0550 | 0.3785 | −0.0790 | 0.2200 |
MUFAs | −0.2830 | < 0.0001 | -0.2900 | < 0.0001 |
PUFAs | 0.3130 | < 0.0001 | 0.3220 | < 0.0001 |
Total cholesterol | 0.2010 | 0.0010 | 0.1700 | 0.0080 |
Triglycerides | −0.0210 | 0.7434 | −0.0490 | 0.4490 |
LDL cholesterol | 0.1950 | 0.0019 | 0.1650 | 0.0110 |
HDL cholesterol | 0.1440 | 0.0217 | 0.1650 | 0.0100 |
VLDL cholesterol | −0.0460 | 0.4703 | −0.0790 | 0.2260 |
Systolic BP | 0.0370 | 0.5550 | 0.0370 | 0.5680 |
Diastolic BP | 0.0020 | 0.9775 | −0.0050 | 0.9330 |
CD4 count | 0.0200 | 0.7723 | 0.0150 | 0.8350 |
Plasma viral load (log10) | −0.0120 | 0.8640 | 0.0050 | 0.9470 |
Years of infection | −0.2230 | 0.0005 | −0.2130 | 0.0010 |
NRTI (m) | −0.1670 | 0.0085 | −0.1710 | 0.0080 |
NNRTI (m) | −0.0510 | 0.5506 | −0.0300 | 0.7330 |
PI (m) | −0.1090 | 0.0864 | −0.1130 | 0.0800 |
AZT exposure (m) | −0.0300 | 0.6352 | −0.0220 | 0.7340 |
AZT exposure (g) | −0.0530 | 0.4058 | −0.0480 | 0.4620 |
d4T exposure (m) | −0.1700 | 0.0074 | −0.1760 | 0.0070 |
d4T exposure (g) | −0.1640 | 0.0097 | −0.1720 | 0.0080 |
ddI exposure (m) | −0.1280 | 0.0437 | −0.1190 | 0.0670 |
EFV exposure (m) | −0.1490 | 0.0182 | −0.1500 | 0.0200 |
NVP exposure (m) | −0.0410 | 0.5164 | −0.0410 | 0.5320 |
BMI = body mass index, WHR = waist-to-hip ratio, HOMA-r, homeostasis model assessment of insulin resistance, MUFAs = monounsaturated fatty acids, PUFAs = polyunsaturated fatty acids, LDL = low density lipoproteín, HDL = high density lipoproteín, VLDL = very low density lipoproteín, BP = blood pressure, NRTI = nucleoside-analogue reverse transcriptase inhibitor, NNRTI = non nucleoside-analogue reverse transcriptase inhibitor; PI = protease inhibitor; AZT = zidovudine, d4T = stavudine, ddI = didanosine, EFV = efavirenz, NVP = nevirapine, m = months; g = grams.