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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Curr Opin Pharmacol. 2010 Aug 26;10(6):613–619. doi: 10.1016/j.coph.2010.08.001

Table 1.

Effect of increasing factor concentration on the EC50 and PAA of glucocorticoid and other steroid receptors

Factor EC50 down EC50 up PAA up PAA down Receptor Reference
GMEB2 x x x x GR, PR [24]
NCoR x x x x AR, GR, PR [23-25,29]
SMRT x x x x AR, GR [23-25,29]
STAMP x x x x GR, PR [24,25]
AIB1 x VDR [45]
cAMP x PML-RAR [47]
β-Catenin x AR [33]
EGF x PR [41]
FoxA1 x x GR [38]
GME x x GR [24]
HDAC2 x GR [39]
HDAC6 x AR [34]
Receptor concentration x PR [40]
Receptor deletions/mutations x x x ER, GR [35,36,60]
SKA2 x GR [37••]
SRC-1 x VDR [45]
TIF2 x x GR, PR, TRb2, VDR [20••,24,27,45,46]
Ubc9 x x GR, PR [24]
Phosphorylation x GR [49•]
PP1α x AR [48•]
XAP2 x GR [50]
FKBP1 x AR [52••]
IL-1β x AR, ER, PR [51]