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. Author manuscript; available in PMC: 2011 Nov 12.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Oct 8;402(2):241–246. doi: 10.1016/j.bbrc.2010.10.006

Fig. 1.

Fig. 1

IL-1β simulated astrocytes release soluble factors in vitro. A. astrocytes treated with IL-1β 20 ng/ml for 2 h induced CCL2 secretion 5.04 fold compared to the control (p<0.001). B. IL-1β treatment induced Interleukin-8 (CXCL8/IL-8) 9.24 fold (p<0.001), C. matrix metalloproteinase-1 (MMP-1) 5.78 fold (p<0.001), D. matrix metalloproteinase-7 (MMP-7) 68.75 fold (p<0.001), E. tumor necrosis factor alpha (TNF-α) 41 fold (p<0.05) and F. transforming growth factor beta 2 (TGF-β2) secretion 1.75 fold compared to their respective controls. Insets in each panel show data from individual representative donor. Values for n represent the number of individual astrocyte donors used for each measurement and calculation of fold changes.