Table 3.
MV | Placebo | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Definite TB | No definite TB | Definite TB | No definite TB | |||||||
N | Mean | N | Mean | P value | N | Mean | N | Mean | P value | |
IFN-γ response, pg/ml | 14 | 191 | 498 | 545 | 0.3533 | 28 | 202.5 | 484 | 435.1 | 0.0080 |
Proliferative index | 13 | 3.8 | 406 | 2.7 | 0.3557 | 27 | 2.7 | 392 | 1.9 | 0.9515 |
Antibody response to LAM, OD | 28 | 0.53 | 797 | 0.61 | 0.5736 | 42 | 0.51 | 773 | 0.47 | 0.7482 |
P values by Mann-Whitney U test
IFN-γ response, interferon gamma response to MV soniciate; LAM, lipoarabinomannan; MV, Mycobacterium vaccae; OD, optical density; proliferation index is defined as the ratio of counts per minute in the well stimulated with MV sonicate over the counts per minute in the medium control well; TB, tuberculosis